[Treatment of hypertension in chronic kidney disease].

Adequate treatment of hypertension in patients with chronic kidney disease reduces the risk of cardiovascular complications, slows down the progression of renal failure, and is an important element in nephroprotection, delaying the onset of renal replacement therapy. Non-pharmacological methods, especially salt restriction, and most of the available antihypertensive medicines are in use. It is often necessary to combine drugs from different groups, among which inhibitors of renin-angiotensin-aldosterone (RAA) system and diuretics are the most important. The choice of an appropriate combination depends on the degree of renal failure, concomitant diseases, extent of proteinuria, and the presence or absence of edema and hypervolemia. Recommended blood pressure is below 140/90 mmHg in patients with proteinuria less than 0.5 g/24 h, and below 130/80 mmHg if daily proteinuria exceeds 0.5 g/24 h.